Associate Research Scientist

Ph.D., Dept. of Experimental Medicine, McGill University, Montreal, Canada.      

M.S.&B.S., Dept. of Biology, Nankai University, Tianjin, China.                                

As technical director of the Yale Stem Cell Center genomics core. Mei collaborates with Dr. Rong Fan's lab to extend the core services into the multiomic field. The PhenoCycler-Fusion system is the fastest spatial biology solution from Akoya bioscience Inc. The system allows unbiased spatial phenotyping of tissues, accounting for every single cell across the whole slide. It can automate cycling and iterative imaging of 100+ biomarkers across the whole slide. Mei has collaborated with many researchers and worked with multiple tissue types, including clinical Formalin-fixed Paraffin Embedded (FFPE) and Fresh Frozen (FF) samples and various tissue types - lymph nodes, tonsil, bone marrow, liver, brain, mitral valve, heart, spleen, kidney, skin and multiple different tumors.

Associate Research Scientist

Ph.D. Bioinformatics, Peking University

Mingyu is a bioinformatics scientist with over 15 years of experience in large-scale multi-omics data analyses including her post-doctoral training in the Fan Lab. she graduated from Peking University under the supervision of Prof. Zemin Zhang. Prior to her graduate study, she was a Bioinformatics Scientist and Group Leader at BGI-Genomics. Besides science, she enjoys music, yoga, dance, and travel.

Associate Research Scientist

Ph.D. in Pathology and Pathophysiology from Zhejiang University.

Prior to joining Fan Lab, Bo focused on researching how LDL (Low Density Lipoprotein) traverses the endothelium to initiate atherosclerosis, a process known as 'Transcytosis,' and the role of cholesterol metabolism in regulating inflammation at VBT, Yale School of Medicine under the guidance of Dr. William Sessa. During his PhD, he investigated how M2 macrophages contribute to the pathology of IPF and aging-related emphysema using various genetically modified mouse models.

At Fan Lab, Bo's interests lie in developing and applying spatial multiomics (DNA-RNA-Protein) approaches to study developmental and pathological diseases

Associate Research Scientist

MD and PhD, Peking University

Fu received his clinical training at Peking University, where he developed a comprehensive understanding of a wide range of clinical diseases. After earning his PhD/MD degree, he served as both an instructor and a physician in Peking University. Following this, he pursued postdoctoral training at Yale Medical School, further enhancing his expertise. Fu's current interests are in the development of innovative tools for spatially-resolved multi-omics. He is dedicated to applying these cutting-edge technologies to practical clinical settings.

Post-doctoral Associate

B.S. Measuring and Control Technology, Tianjin University, 2015

Ph.D. Instrument Science and Technology, Tianjin University, 2021

Zhiliang worked as a visiting research assistant at Fan Lab from 2018 to 2020, during which he gained a deep passion on microfluidics, single-cell technologies, and cancer immunotherapy. He is currently working on single-cell multi-omics characterization of CAR T infusion products, the development of spatial immune repertoire technology, spatial alternative splicing profiling technology, and the next-generation spatial technology. He enjoys working out and reading books in his spare time.

Post-doctoral Associate

Di is focusing on spatial multiomics research and likes traveling in her spare time.

Post-doctoral Associate

Xiaolong received his Ph.D. from Fudan University in 2022, focusing on antibody development and antibody repertoire analysis for infectious diseases. He is presently under the joint mentorship of Rong Fan and Sidi Chen, dedicating his efforts to pioneering spatial omics technologies, including spatial glycomics and spatial CRISPR. His research aims to elucidate the mechanisms underlying cancer development and to advance targeted cancer immunotherapies.

Post-doctoral Associate

B.S. Biological Sciences (Honors Program), Shanghai Jiao Tong University, 2019

Ph.D. Molecular Genetics and Genomics, Washington University in St. Louis, 2023

Haikuo was trained in diverse biological fields including immunology, genetics, systems biology and nephrology. During his Ph.D. study advised by Dr. Ben Humphreys, Haikuo employed split-pool barcoding multiomics approaches to study kidney heterogeneity and tissue fibrosis. At the Fan Lab, Haikuo is interested in studying how gene transcription events are regulated in health and disease, and the underlying spatiotemporal dynamics and epigenetic mechanisms. He likes reading and writing outside of the lab.

Post-doctoral Associate

PhD, UC San Diego

Anthony "Tony" received his PhD from the University of California San Diego in 2023 under the guidance of Dr. Lingyan Shi in the Shu-Chien Gene-Lay Department of Bioengineering. He studied biomedical imaging applications and analysis with a specialization in label-free vibrational spectromicroscopy modalities such as Stimulated Raman Scattering. After using the label-free multi-modal imaging platform he set up to study subcellular breast cancer metabolism and diabetic kidney disease, he co-founded Raman Noodle Inc. - a metabolic imaging contract research organization and consultation agency. Tony's current interests center on the integration of spatial omics research and microscopy modalities to elucidate the interplay between biomolecular metabolism and biological fate.

Post-doctoral Associate

B.S., Biological Sciences, Nanjing University, 2017

Ph.D., Genetics, Yale University, 2023

Miao received her Ph.D. under the guidance of Dr. Siyuan (Steven) Wang. During the Ph.D. study, Miao developed an imaging-based method named “Multiplexed Imaging of Nucleome Architectures” (MINA) that can profile 3D chromatin folding, RNA expression and protein localization in single cells in tissues. Miao further studied the evolutionary changes in 3D genome during lung and pancreatic cancer progression and explored the potential of single-cell cancer 3D genome mapping in providing candidate therapeutic targets and biological insights. Currently, Miao is interested in integrating spatial multi-omics sequencing with optical imaging techniques to study tissue development and diseases. In her spare time, she enjoys reading, writing and spending time with family and friends.

PhD Student

B.S. Biological Sciences, University of Science and Technology of China

Xiaoyu is interested in developing new tools for spatially-resolved multi-omics sequencing, and characterizing the hematopoietic niche within its spatial context. When she’s not doing research, you may find her being outdoors, traveling, or reading about everything.

PhD Student

B.Eng., Huazhong University of Science and Technology

Shuozhen is currently working on applying spatial omics techniques to cancers including glioblastoma and pancreatic ductal adenocarcinoma. She hopes one day she could help patients with the innovative techniques she develops. She enjoys playing table tennis, reading novels, and eating in her leisure time.

PhD Student

B.S. Biomedical Engineering, Yale University 2020

Archie first joined the Fan Lab during his undergraduate studies applying spatial omics technologies to study the mouse lymph node microenvironment. As a graduate student in the Fan Lab, his work is focused on mapping senescent cells in lymphoid tissues as part of the NIH’s Cellular Senescence Network (SenNet) Consortium. In his spare time, he enjoys cooking, and playing FIFA, and is a big fan of Liverpool FC.

PhD Student

B.S. Medical Sciences, Shahid Behesti University, 2015

Negin gained a deep appreciation of cancer, radiotherapy and medical physics and found her passion in biomedical Engineering. In the Fan lab, she works on spatial transcriptomic and multiomic mapping human and mouse liver to profile liver zonation and study Senescence and immune cells as well as complex metabolism involved in several key liver functions. In her spare time, she enjoys working out, playing tennis, and musical instruments.

PhD Student

B.S. Engineering Sciences, Princeton University 2018

Alev worked as a research affiliate in both Christophe Benoist's group at Harvard Medical School and The Broad Institute until 2021. During this time, she also became an active member of The Immunological Genome Project and pursued her Master’s in Data Science. In the Fan lab, she hopes to develop spatial CRISPR-screening technology to determine spatial multiomics heterogeneity in the context of disease. When she isn’t in the lab, she likes to play ice hockey, soccer, ski and run. She also enjoys cooking, spending time with family and friends, and traveling.

PhD Student

B.S. Mathematics, Fudan University

M.S. Biostatistics, Johns Hopkins University

Before joining Fan Lab, Yao spend a few years doing research in cancer and cardiovascular disease. She is specially interested in multi-omics, spatial transcriptomics, and advanced algorithms in this field. She is now a member of the SenNet project and hopes to use spatial transcriptomics to decode secrets in aging and age-related diseases, such as cancer. She also enjoys reading novels and searching for nice restaurants in her spare time.

PhD Student

B.S. Bio-Convergence and Nano Science & Engineering, Yonsei University, 2022

Jungmin is working on profiling mouse lymph nodes using spatial transcriptomics and multiplexed tissue imaging. Outside of the lab, she enjoys knitting, playing the violin, pilates, and reading.

PhD student

B.S. University of Arizona, 2022

Zixi first joined the Fan Lab for her summer internship in the summer of 2019 when she was in her undergraduate study. With her growing interest in applying spatial transcriptomics techniques to various neurological diseases, she worked as a postgraduate researcher in the Fan lab from 2024 to 2025. In the Fan Lab, she hopes to continue exploring how spatial transcriptomics techniques can help us reveal the homogeneity of specific neurological and neuropsychiatric disorders in neuroinflammatory pathways.

2025 PEB Intern

Anusree is majoring in Biomedical Engineering at Stony Brook University, where she is set to graduate in May 2028. Her research interests center on medical innovation, and through this lab, she has developed a strong appreciation for senescence and epigenomic research. During her time here, Anusree gained experience in image analysis using MATLAB, conducted thorough literature reviews, shadowed wet lab experiments, and deepened her understanding of senescence and core experimental and analysis techniques

2025 SenNet Intern

Evan currently studies Biomedical Engineering at the University of Wisconsin–Madison. His current research focuses on mapping cellular senescence in human and mouse liver using spatial omics technologies. Evan combines high-dimensional image analysis in MATLAB and R with insights from transcriptomic and epigenomic profiling to investigate how senescent cells contribute to liver disease. In his free time, he enjoys running in East Rock Park and the New Haven food scene.

2025 Summer Intern

Shane is a current high school student attending Western Reserve Academy, where he devotes his research interest to the Cancer Immunology class. His current project focuses on a machine learning approach to identify key biomarkers in triple-negative breast cancer within a multi-omics framework. During his internship in the lab, he learns the fundamentals of spatial and single-cell biology and explores the mutation pathway in angioimmunoblastic T-cell lymphoma with his mentor Archie. Shane enjoys playing tennis with his friends and discovering great restaurants in his free time.

2025 Summer Intern

Emily is a junior from Palo Alto, California majoring in Molecular, Cellular, and Developmental Biology. She is very interested in the epigenetic control of gene expression as well as non-canonical aspects of transcription and translation. At the Fan Lab, Emily is investigating the spatial dynamics of gene transcription using spatial CUT&Tag to profile serine phosphorylations in the C-terminal domain of RNA Polymerase II. In her free time, Emily loves playing the viola, singing, reading, and writing.